Jv. Allen et al., ENANTIOSELECTIVE PALLADIUM-CATALYZED ALLYLIC SUBSTITUTION - ELECTRONIC AND STERIC EFFECTS OF THE LIGAND, Tetrahedron : asymmetry, 5(10), 1994, pp. 1895-1898
Ligands containing an enantiomerically pure oxazoline and a sulfur-con
taining tether have been examined for their ability to provide asymmet
ric induction in palladium catalysed allylic substitution reaction. Th
e enantioselectivity obtained was found to be highly dependent upon th
e stereochemistry at sulfur (for sulfoxides), and also somewhat depend
ent upon the nature of the aryl group attached to the sulfur.