Effect of amantadine on weight gain during olanzapine treatment

Authors
Floris, M Lejeune, J Deberdt, W
Citation
M. Floris et al., Effect of amantadine on weight gain during olanzapine treatment, EUR NEUROPS, 11(2), 2001, pp. 181-182
Citations number
4
Categorie Soggetti
Neurosciences & Behavoir
Journal title
EUROPEAN NEUROPSYCHOPHARMACOLOGY
ISSN journal
0924977X → ACNP
Volume
11
Issue
2
Year of publication
2001
Pages
181 - 182
Database
ISI
SICI code
0924-977X(200104)11:2<181:EOAOWG>2.0.ZU;2-9
Abstract
Patients treated with olanzapine may gain weight, especially in the first m onths of therapy. Amantadine (100-300 mg/day) was started in 12 patients ha ving a mean weight gain of 7.3 kg during olanzapine treatment. The patients ' weight stabilised and over 3-6 months they lost an average of 3.5 kg. No clinical deterioration occurred and no adverse effects were reported. These observations merit confirmation in randomised, controlled trials. (C) 2001 Elsevier Science B.V. All rights reserved.