Presence of ochratoxin A in human milk in relation to dietary intake

Individual and geographical variations in ochratoxin A (OA) levels in human blood and milk samples may be due to differences in dietary habits. The pu rpose of this study was to examine the relationship between OA contaminatio n of human milk and dietary intake. Human milk samples were collected from 80 Norwegian women. The usual food intake during the last year was recorded using a quantitative food frequency questionnaire. The concentration of OA in the human milk was determined by HPLC (detection limit 10 ng/l). Sevent een (21%) out of 80 human milk samples contained OA in the range 10-182 ng/ l. The women with a high dietary intake of liver paste (liverwurst, liver p ate) and cakes (cookies, fruitcakes, chocolate cakes, etc.) were more likel y to have OA-contaminated milk. The risk of OA contamination was also incre ased by the intake of juice (all kinds). In addition, the results indicate that breakfast cereals, processed meat products, and cheese could be import ant contributors to dietary OA intake. OA contamination of the milk was unr elated to smoking, age, parity, and anthropometric data other than body wei ght.