Objectives: To determine the difference in aspiration rates between gastric
ally and transpylorically fed patients in the intensive care unit.
Design: A prospective controlled study of critically ill patients randomize
d to receive either a gastrically placed feeding tube or a transpylorically
placed feeding tube,
Setting: University teaching hospital's medical intensive care unit, The st
udy was conducted over 14 months.
Patients: Fifty-four critically ill subjects (with an overall 40% mortality
) with similar baseline age, severity of illness, and nutritional needs req
uiring enteral nutrition, with 51 completing the study.
Interventions: All feeds were tagged with technetium-99m radiolabeled sulfu
r colloid, and the pulmonary secretions or lungs of each patient were scann
ed on a daily basis to determine whether aspiration had occurred. Patients
were fed according to their assigned tube placement which was verified dail
y by continuous electromyography.
Measurements and results: Of 27 gastrically fed patients 2 (7%) had evidenc
e of scanned feed in pulmonary secretions or the lung, compared to 3 of 24
(13%) transpylorically fed patients (n.s.). Clinical suspicion of aspiratio
n was insensitive and detected only 60% of isotopically documented aspirati
ons with a positive predictive value of 27%.
Conclusion: There was no difference in aspiration rates between gastrically
and transpylorically fed critically ill patients.