Although skeletal muscle is capable of oxidizing selected amino acids, exer
cise in the fed and carbohydrate-replete condition results in only a small
increase in amino acid utilization. Nevertheless, it may be important to in
crease the dietary protein requirements of active individuals. There is ong
oing debate as to whether the amino acids for oxidation are derived from th
e free amino acid pool, from net protein breakdown, or a combination of bot
h. There has been interest in the potential ergogenic benefits of amino aci
d ingestion; however, BCAA ingestion does not appear to affect fatigue duri
ng prolonged exercise, there is little support from controlled studies to r
ecommend glutamine ingestion for enhanced immune function, and although glu
tamine stimulates muscle glycogen synthesis, its addition to carbohydrate s
upplements provides no additional benefit over ingestion of carbohydrate al
one.