Risk far tuberculosis infection among internally displaced persons in the Republic of Georgia

OBJECTIVE: TO determine the prevalence of tuberculosis (TB) infection and d isease among internally displaced persons residing in Tbilisi, Republic of Georgia. DESIGN: Residents of eight refugee hostels were screened for TB infection u sing a tuberculin skin test (TST) and a symptom questionnaire. participatio n was voluntary. TST-positive individuals were referred for chest radiograp hy. Subjects with cough, fever, or night sweats of >2 weeks duration provid ed sputum for acid-fast bacilli (AFB) microscopy and culture. RESULTS: Of approximately 4000 potential subjects (internally displaced per sons), 988 (24.7%) participated in the screening program. Of these 988, 931 (94.2%) who had a TST placed returned at 48-72 hours to have the skin test examined; 447 (48.0%) were TST-positive (greater than or equal to 10 mm in duration). In multivariate analysis, risk factors for a positive TST includ ed male sex, ever having received BCG, history of close contact with a case of active tuberculosis, and living in one specific refugee hostel. Risk fo r a positive TST was greater among subjects >20 years old, but there was no difference between age groups over the age of 20 years. Five patients with active TB were identified through the screening program, giving a case rat e of 537 per 100 000 population. CONCLUSION: Tuberculosis infection and disease were common in this group of internally displaced persons. Screening was a useful mechanism of case fin ding among this high prevalence population.