Ahrw. Simpson et al., Chronic osteomyelitis - The effect of the extent of surgical resection on infection-free survival, J BONE-BR V, 83B(3), 2001, pp. 403-407
Citations number
18
Categorie Soggetti
Ortopedics, Rehabilitation & Sport Medicine","da verificare
We studied prospectively a consecutive series of 50 patients with chronic o
steomyelitis. Patients were allocated to the following treatment groups: 1)
wide resection, with a clearance margin of 5 mm or more; 2) marginal resec
tion, with a clearance margin of less than 5 mm; and 3) intralesional biops
y, with debulking of the infected area. All patients had a course of antibi
otics, intravenously for six weeks followed by orally for a further six wee
ks. No patients in group 1 had recurrence, In patients treated by marginal
resection (group 2), 8 of 29 (28%) had recurrence. All patients who had deb
ulking had a recurrence within one year of surgery. We performed a survival
analysis to determine the time of the recurrence of infection. In group 2
there was a higher rate of recurrence in type-B hosts (p < 0.05); no type-A
hosts had recurrence. This information is of use in planning surgery for c
hronic osteomyelitis.