The present study examined the efficacy of fluvoxamine in the treatmen
t of trichotillomania (TM) and coexistent clinical features. Twenty-on
e participants with a principal diagnosis of TM were given fluvoxamine
in a 12-week open trial, For 13 patients who completed treatment, sig
nificant improvement was noted on only a few measures of hair pulling,
End-state analyses for the entire group of participants, however, dem
onstrated significant improvement in measures of distress, duration, c
ontrol, and resistance. Significant decreases over treatment were also
found on measures of coexistent anxiety for both the completer and th
e entire participant groups; depressive symptoms improved for complete
rs. Conclusions about the effectiveness of fluvoxamine for treatment o
f TM cannot be drawn, given the uncontrolled nature of the study; howe
ver, end-state analyses suggest the potential utility of fluvoxamine i
n a subset of patients with TM.