Preparation of novel 2-(benzo[b]furan-2-yl)-1H-imidazolines for photoaffinity labelling and affinity isolation of imidazoline binding proteins

Authors
Clews, J Morgan, NG Ramsden, CA
Citation
J. Clews et al., Preparation of novel 2-(benzo[b]furan-2-yl)-1H-imidazolines for photoaffinity labelling and affinity isolation of imidazoline binding proteins, J HETERO CH, 38(2), 2001, pp. 519-521
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
38
Issue
2
Year of publication
2001
Pages
519 - 521
Database
ISI
SICI code
0022-152X(200103/04)38:2<519:PON2FP>2.0.ZU;2-2
Abstract
The preparations of 5-aminoefaroxan 8 and 5-azidoefaroxan 9, which retain t he capacity to stimulate insulin secretion via the putative I-3 imidazoline receptor and are useful biological tools for affinity chromatography studi es and photoaffinity labelling studies of imidazoline binding proteins, are described.