We study the bulk effective theory of a class of orbifolds of the type-IIB
string with D5-branes, compactified to four dimensions. These constructions
are connected, in a region of their moduli space, to some orbifolds of the
type-I and heterotic string. We compare the effective actions through the
coupling of the R-2 term, and we argue that these orbifolds provide non-per
turbative deformations of the latter, in which the gauge group is entirely
non perturbative.