PURPOSE: To determine characteristic features of peripheral cholangioc
arcinoma on two-phase spiral computed tomographic (CT) scans. MATERIAL
S AND METHODS: Thirty-four patients with peripheral cholangiocarcinoma
underwent two-phase spiral CT. Hepatic arterial phase and portal veno
us phase images were obtained 30 and 65 seconds, respectively, after t
he start of contrast material infusion. RESULTS: Thin, mild, incomplet
e rimlike contrast enhancement at the tumor periphery was seen on CT s
cans from both phases in 23 patients. Thick, continuous rimlike contra
st enhancement and marked homogeneous contrast enhancement were presen
t on scans in four patients and one patient, respectively, No definite
contrast enhancement pattern was seen on scans in six patients. Other
findings included increased lobar or segmental hepatic attenuation in
adjacent normal liver during the arterial phase (n = 10), markedly lo
w attenuation with amorphous areas of slightly high attenuation in the
tumor during both phases (n = 33), internal septumlike linear structu
res (n = 8), narrowing or obstruction of the portal vein as it travers
ed the tumor (n = 16), and a patent hepatic vein (n = 4). CONCLUSION:
Thin, mild, incomplete rimlike contrast enhancement at the tumor perip
hery and markedly low intratumoral attenuation with amorphous areas of
slightly high attenuation during both scanning phases are typical fin
dings of peripheral cholangiocarcinoma.