M. Natoli et al., A STUDY OF CATALYTIC P-CYCLODEXTRIN CARBONATE MEMBRANE REACTOR PERFORMANCE IN PNPA HYDROLYSIS, Journal of molecular catalysis. A, Chemical, 121(2-3), 1997, pp. 179-186
A catalytic cyclodextrin membrane reactor system is a promising tool f
or the production of chemicals of potential interest. To investigate t
he application of membrane immobilized carbonate derivative beta-cyclo
dextrin (beta-CD) for the p-nitrophenylacetate (PNPA) hydrolysis, the
effect of different average degree of beta-CD carbonate substitution (
DS), the amount of immobilized beta-CD carbonate and operating conditi
ons such as pH and temperature have been examined under a constant sub
strate concentration. The initial reaction rate as a function of immob
ilized beta-CD carbonate concentration resulted in an increase of the
p-nitrophenol (PNP) production rate. A complete hydrolysis of PNPA was
reached after 3 h of operation by using the beta-CD carbonate with DS
equal to 7. These data suggest the conditions under which the beta-CD
carbonate membrane reactor with 2.5 wt% to 7.5 wt% of beta-CD carbona
te (DS 5 and 7) can operate with high productivity and low cost: a rea
ction temperature of 20 degrees C, a pH of 8.4, low permeation rate an
d transmembrane pressure.