The Ludwigshafen myocardial infarction project has demonstrated, that an in
tense public media campaign can reduce prehospital delays in acute myocardi
al infarction. With an additional intrahospital improvement, this can lead
to a better and more frequent use of recanalization (thrombolysis or percut
aneous transluminal coronary angioplasty [PTCA]).
Several large multicentric registries (60 minutes myocardial infarction pro
ject, MIR, MITRA) with a total of about 40,000 patients at over 300 hospita
ls in Germany showed, that intrahospital improvement of infarction therapy
can also be achieved in other hospitals. Voluntary participation in an infa
rction registry leads to quality control and improvement. Two factors are e
specially important: (1) documentation of every infarction patient, and (2)
documentation of the reasons why therapy was given or withheld in every si
ngle patient. The improvement in early therapy is associated with a 20% red
uction of hospital mortality (MITRA-1). The media campaign in Ludwigshafen
to reduce prehospital patient delay, however, could not yet be carried out
in other areas effectively and intensely enough.