IDENTIFICATION OF THERMAL-OXIDATION PRODUCTS OF CHOLESTERYL ACETATE

The polar products separated by solid-phase extraction from the peroxi dation mixture of cholesteryl acetate, were investigated. The oxidatio n products were identified by comparing GC retention times as well as the mass spectra against those of available or synthesized standards. The main oxidation products where 7 beta-chydroperoxicholesteryl aceta te, 7 alpha-hydroperoxicholesteryl acetate, 7-ketocholesteryl acetate, the alpha and beta isomers of 7-hydroxycholesteryl acetate, the alpha - and beta-epoxy isomers in 5,6 position and several derivatives from the loss of groups (especially the acetic and/or hydroxyl groups in th e form of acetic acid and water).