Atropo-enantioselective ring cleavage of Lewis acid modified biaryl thionolactones

Authors
Bringmann, G Wuzik, A Kummel, J Schenk, WA
Citation
G. Bringmann et al., Atropo-enantioselective ring cleavage of Lewis acid modified biaryl thionolactones, ORGANOMETAL, 20(8), 2001, pp. 1692-1694
Citations number
32
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANOMETALLICS
ISSN journal
02767333 → ACNP
Volume
20
Issue
8
Year of publication
2001
Pages
1692 - 1694
Database
ISI
SICI code
0276-7333(20010416)20:8<1692:ARCOLA>2.0.ZU;2-T
Abstract
Attachment of an achiral, ruthenium-based Lewis acid fragment to configurat ionally unstable biaryl thionolactones la-lc, atropo-enantioselective reduc tive lactone cleavage of the resulting complexes with chiral hydride reagen ts, and subsequent decomplexation leads to axially chiral thioethers 3a-3c with enantiomeric ratios of up to 92:8.