Studies on the Wittig reaction (XXX): Stereoselective synthesis and bioactivity of 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes

Authors
Lu, SM Xiao, WJ Huang, WF Wu, TJ
Citation
Sm. Lu et al., Studies on the Wittig reaction (XXX): Stereoselective synthesis and bioactivity of 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes, PHOSPHOR SU, 167, 2000, pp. 195-203
Citations number
22
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
ISSN journal
10426507 → ACNP
Volume
167
Year of publication
2000
Pages
195 - 203
Database
ISI
SICI code
1042-6507(2000)167:<195:SOTWR(>2.0.ZU;2-4
Abstract
Twelve 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes 4 were synthesized by N-alky lation of alkenyl bromides 3, which were obtained by the Wittig reaction of 5-hydroxypentyltriphenylphosphonium bromide 1 with various aromatic aldehy des and subsequent bromination of the resulting alkenyl alcohols 2. The pre liminary bioassay results showed that new compounds 4 were active to file p lant diseases.