Sm. Lu et al., Studies on the Wittig reaction (XXX): Stereoselective synthesis and bioactivity of 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes, PHOSPHOR SU, 167, 2000, pp. 195-203
Citations number
22
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Twelve 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes 4 were synthesized by N-alky
lation of alkenyl bromides 3, which were obtained by the Wittig reaction of
5-hydroxypentyltriphenylphosphonium bromide 1 with various aromatic aldehy
des and subsequent bromination of the resulting alkenyl alcohols 2. The pre
liminary bioassay results showed that new compounds 4 were active to file p
lant diseases.