Human immunoglobulin for diabetic amyotrophy - a promising prospect?

Diabetic neuropathies are universally recognised and cause significant morb idity. At present improving glycaemic control is the only recognised treatm ent. A man with type 2 diabetes presented with disabling asymmetric lower L imb proximal neuropathy. Rapid clinical, functional, and electrical improve ment followed treatment with intravenous Immunoglobulin. The aetiology of d iabetic amyotrophy remains controversial but there is evidence for an immun e mediated process and this case suggests a role for immunoglobulin in the management of this debilitating condition.