Preventive strategies for hereditary breast cancer pre-disposition

First retrospective data show that hereditary Breast cancer risk can be pos itively influenced by prophylactic surgical procedures and hereby a thoroug h consultation seem to be an option for m uta nt g en e carriers. A fi rst evaluation of the women of 1050 high-risk families by the German Consortium "Hereditary Breast and Ovarian Cancer promoted by the German Cancer Aid (D eutsche Krebshilfe)" has shown that approximately 80% of the women concerne d decide to participate in an intensive early detection - programme and onl y 5% of the women have decided to submit themselves to prophylactic surgica l measures. Th is again shows how absolutely necessary the elaboration and evaluation of early detection measures within the different investigation p rojects are.