Asymmetric synthesis of a nitroalkane by the use of novel nitroalkene reductases from baker's yeast

Authors
Kawai, Y Inaba, Y Hayashi, M Tokitoh, N
Citation
Y. Kawai et al., Asymmetric synthesis of a nitroalkane by the use of novel nitroalkene reductases from baker's yeast, TETRAHEDR L, 42(19), 2001, pp. 3367-3368
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
19
Year of publication
2001
Pages
3367 - 3368
Database
ISI
SICI code
0040-4039(20010507)42:19<3367:ASOANB>2.0.ZU;2-1
Abstract
Two kinds of novel nitroalkene reductases were isolated from baker's yeast. Reduction of a trisubstituted nitroalkene by these reductases afforded the corresponding nitroalkane with excellent enantioselectivity, moderate dias tereoselectivity, and in good yield. (C) 2001 Elsevier Science Ltd. All rig hts reserved.