Synthesis of 5-substituted indole derivatives. Part 3: A facile synthesis of 5-chloromethyl-1H-indole-2-carboxylates: replacement of sulfonic acid functionality by chlorine

Authors
Pete, B Toke, L
Citation
B. Pete et L. Toke, Synthesis of 5-substituted indole derivatives. Part 3: A facile synthesis of 5-chloromethyl-1H-indole-2-carboxylates: replacement of sulfonic acid functionality by chlorine, TETRAHEDR L, 42(19), 2001, pp. 3373-3375
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
19
Year of publication
2001
Pages
3373 - 3375
Database
ISI
SICI code
0040-4039(20010507)42:19<3373:SO5IDP>2.0.ZU;2-X
Abstract
Valuable new synthetic intermediates, 5-chloromethyl-1H-indole-2-carboxylat es, were prepared by the elimination of SO2 from 2-ethoxycarbonyl-1H-indole -5-methanesulfonic acids, which are easily accessible by Fischer-type indol ization. (C) 2001 Elsevier Science Ltd. All rights reserved.