Topographical micropatterning of poly(dimethylsiloxane) using laminar flows of liquids in capillaries

Authors
Takayama, S Ostuni, E Qian, XP McDonald, JC Jiang, XY LeDuc, P Wu, MH Ingber, DE Whitesides, GM
Citation
S. Takayama et al., Topographical micropatterning of poly(dimethylsiloxane) using laminar flows of liquids in capillaries, ADVAN MATER, 13(8), 2001, pp. 570
Citations number
20
Categorie Soggetti
Multidisciplinary,"Material Science & Engineering
Journal title
ADVANCED MATERIALS
ISSN journal
09359648 → ACNP
Volume
13
Issue
8
Year of publication
2001
Database
ISI
SICI code
0935-9648(20010418)13:8<570:TMOPUL>2.0.ZU;2-5
Abstract
"Micro-landscapes" suitable for investigating the behavior of living cells under different stimuli are cast from poly(dimethylsiloxane) by simultaneou sly etching a slab and a relief (see Figure) with a Bu4NF solution and flus hing out dissolved material with N-methylpyrrolidone. It is crucial that al l liquid streams during the etching process are laminar. Various accessible topographies for the relief and examples of applications are given.