Zeamatin is a 22-kDa protein isolated from Zea mays that has antifungal act
ivity against human and plant pathogens. Unlike other pathogenesis-related
group 5 proteins, zeamatin inhibits insect a-amylase and mammalian trypsin
activities. It is of clinical significance that zeamatin did not inhibit hu
man alpha -amylase activity and inhibited mammalian trypsin activity only a
t high molar concentrations.