The effect of additional autopolyploidization in a slow growing cellulase hyperproducer of Trichoderma

M14-2 is a cellulase hyperproducer derived from Trichderma reesei QM 6a, bu t with a growth rate lower than that of the original strain. When M14-2 was autopolyploidized followed by haploidization and selection, the strain wit h both a higher cellulase productivity per mycelia and a higher growth rate could be obtained as M14-2B. This strain seemed to be constructed using ge ne sources amplified by additional autopolyploidization.