Regional and temporal progression of reactive astrocytosis in the brain ofthe myelin mutant taiep rat

Authors
Chavez, BAL Guevara, J Galindo, S Luna, J Ugarte, A Villegas, O Mena, R Eguibar, JR Martinez-Fong, D
Citation
Bal. Chavez et al., Regional and temporal progression of reactive astrocytosis in the brain ofthe myelin mutant taiep rat, BRAIN RES, 900(1), 2001, pp. 152-155
Citations number
13
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
900
Issue
1
Year of publication
2001
Pages
152 - 155
Database
ISI
SICI code
0006-8993(20010504)900:1<152:RATPOR>2.0.ZU;2-V
Abstract
Reactive astrocytosis in taiep rats was shown by glial fibrillary acidic pr otein (GFAP) immunoreactivity measured by means of enzyme-linked immunosorb ent assay and indirect immunofluorescence. Increased GFAP immunoreactivity was first observed in the brainstem of 15-day-old taiep rats and was widesp read throughout all brain regions at 6 months of age. Characteristically, a strocytes were hypertrophic and displayed strong GFAP fluorescence. The pat tern of these reactive cells may correlate with the process of dysmyelinati on in the taiep rat. (C) 2001 Published by Elsevier Science B.V.