A 33-year old woman with nitroimidazole-resistant vaginal trichomoniasis is
described. She was treated with intravaginal paromomycin (500 mg daily for
2 days). This cured the trichomoniasis but resulted in severe local side e
ffects. Paromomycin may he useful for difficult cases of nitroimidazole-res
istant Trichomonas vaginalis vaginitis. The exact dosage still has to be de
termined. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.