Synthesis of some new 1,5-benzothiazepines containing 2H-1-benzopyran-2-one heterocycle

Authors
Prashant, A Rao, SS Chowdary, KS Krishnan, VSH
Citation
A. Prashant et al., Synthesis of some new 1,5-benzothiazepines containing 2H-1-benzopyran-2-one heterocycle, HETEROCYC C, 7(1), 2001, pp. 61-66
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLIC COMMUNICATIONS
ISSN journal
07930283 → ACNP
Volume
7
Issue
1
Year of publication
2001
Pages
61 - 66
Database
ISI
SICI code
0793-0283(2001)7:1<61:SOSN1C>2.0.ZU;2-7
Abstract
A facile procedure has been developed for the synthesis of 2-aryl/heteryl-4 -(2H-1-benzopyran-2-one-8-yl)-2,3-dihydro-1,5-benzothiazepines (5a-o) by th e reaction of 1-(2H-1-benzopyran-2-one-8-yl)-3-aryl/heteryl-2-propenones (3 a-k) with 2-aminothiophenols (Ja,b) in toluene in the presence of triflouro acetic acid.