Comparison of sequence analysis and the INNO-LiPA HBV DR line probe assay for detection of lamivudine-resistant hepatitis B virus strains in patientsunder various clinical conditions

Authors
Aberle, SW Kletzmayr, J Watschinger, B Schmied, B Vetter, N Puchhammer-Stockl, E
Citation
Sw. Aberle et al., Comparison of sequence analysis and the INNO-LiPA HBV DR line probe assay for detection of lamivudine-resistant hepatitis B virus strains in patientsunder various clinical conditions, J CLIN MICR, 39(5), 2001, pp. 1972-1974
Citations number
15
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
39
Issue
5
Year of publication
2001
Pages
1972 - 1974
Database
ISI
SICI code
0095-1137(200105)39:5<1972:COSAAT>2.0.ZU;2-5
Abstract
A line probe assay (INNO-LiPA HBV BR) detecting drug-resistant hepatitis B virus (HBV) strains was evaluated, Results concordant with sequence analysi s were obtained with 48 of 56 serum samples from HBV-infected patients unde rgoing lamivudine therapy. In eight cases, additional minor subpopulations could be identified by the line probe assay.