Recent advances in the chemistry of fullerene have allowed the synthesis of
many classes of novel fullerene derivatives. Among these classes, fulleren
e-based amino acids and peptides are particularly interesting, both for str
uctural studies and biological applications. In this review, we mill discus
s our own achievements in this rapidly growing field. In particular, the ap
plication of fulleroproline (Fpr) amino acids and peptides to medicinal che
mistry and material science will be highlighted. Copyright (C) 2001 Europea
n Peptide Society and John Wiley & Sons, Ltd.