Solvent effects on aza-anionic cycloaromatization of 2-(2-substituted-ethynyl)benzonitriles

Authors
Lin, CF Yang, JH Hsieh, PC Lu, WD Wu, MJ
Citation
Cf. Lin et al., Solvent effects on aza-anionic cycloaromatization of 2-(2-substituted-ethynyl)benzonitriles, J CHIN CHEM, 48(2), 2001, pp. 211-214
Citations number
13
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
ISSN journal
00094536 → ACNP
Volume
48
Issue
2
Year of publication
2001
Pages
211 - 214
Database
ISI
SICI code
0009-4536(200104)48:2<211:SEOACO>2.0.ZU;2-C
Abstract
The methanolysis of 2-(2-aryl ethynyl)benzonitriles is accelerated when the polar aprotic solvents are added, which could enhance the 6-endo pathway a nd give isoquinolones, though the 5-exo pathway is occupied mostly. The yie lds of products would also be increased.