NMR studies of the conformational behaviour and tautomerism of bis- and tris-saccharidoguanidines

Authors
Toth, G Gati, T Pinter, I Kovacs, J Haessner, R
Citation
G. Toth et al., NMR studies of the conformational behaviour and tautomerism of bis- and tris-saccharidoguanidines, MAGN RES CH, 39(5), 2001, pp. 283-287
Citations number
26
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
MAGNETIC RESONANCE IN CHEMISTRY
ISSN journal
07491581 → ACNP
Volume
39
Issue
5
Year of publication
2001
Pages
283 - 287
Database
ISI
SICI code
0749-1581(200105)39:5<283:NSOTCB>2.0.ZU;2-F
Abstract
The reaction of an acetyl-protected symmetrical sugar carbodiimide with ami nes yielded the corresponding trisubstituted guanidine derivatives 2-6 with two or three sugar units. Their tautomerism, isomerism and conformational behaviour were elucidated by application of one- and two-dimensional H-1 an d C-13 NMR spectroscopy. The rate of tautomerisation was calculated from RO ESY exchange measurements. Copyright (C) 2001 John Wiley & Sons, Ltd.