Proliferation index is related to patient age in glioblastoma

Younger patients with glioblastomas have a significantly better prognosis t han do older patients. To determine whether patient age might be related to proliferation of glioblastoma cells, glioblastomas from patients of differ ent ages were stained with the Molecular Immunology Borstel number 1 antibo dy to detect proliferating cells. Younger patient age was a significant pre dictor of a low Molecular Immunology Borstel number 1 proliferation index ( p = 0.0001). This previously unreported association favors an intrinsic dif ference in the type of glioblastomas that afflict younger patients.