Twelve patients with brain tumors and progressive edema caused by tumor pro
gression or radiochemotherapy-related leukoencephalopathy were treated with
H15, a phytotherapeutic anti-inflammatory agent. Edema was reduced in two
of seven patients with glioblastoma with tumor progression and in three of
five patients with treatment-related leukoencephalopathy. All patients with
leukoencephalopathy improved clinically for several months.