Entamoeba histolytica is a well-recognized cause of infectious colitis and
disseminated amebic abscesses. Most prevalent in the tropics and subtropics
, E. histolytica infections may also occur in the developed world. We descr
ibe a case of a North American traveler with intestinal amebiasis, a diagno
sis first made by colonic biopsy. We review the available diagnostic tools
and the role of the surgical pathologist in the detection of this infection
.