Cutis marmorata telangiectatica congenita: Laser Doppler fluxmetry evidence for a functional nervous defect

We report a 5-month-old infant with cutis marmorata telangiectatica congeni ta (CMTC) without associated abnormalities and unusual hemicorporal vascula r markings. Laser Doppler fluxmetry of the involved skin, carried out for t he first time, and the measurement of the transcutaneous partial pressure o f oxygen indicate a functional disturbance, which may be the expression of an alpha -adrenergic innervation deficit of the cutaneous terminal blood ve ssels.