This essay discusses resonances that occur when multi-electron atoms and mo
lecules are exposed to intense laser fields. The subject owes much to the f
undamental studies by Ugo Fano on the interference of autoionizing states w
ith continua giving rise to asymmetric peaks in excitation spectra. The app
roach adopted is based on R-matrix Floquet theory, a nonperturbative ah ini
tio method, which has been used to describe in a unified way a wide range o
f multiphoton processes. The theory is illustrated by presenting results ob
tained for resonances in the multiphoton spectra of He, Ar, and H-2. Finall
y, the essay concludes by considering possible future directions of researc
h.