The authors investigated the prevalence of multiple medically unexplained s
ymptoms (MMUS) as identified by primary care physicians (PCPs) in a systema
tic sample of 172 patients. Patients were from a university-affiliated urba
n primary care practice serving a low-income population. Patients with a hi
story of MMUS were older (mean: 57.2 vs. 53.0 years), more likely to be fem
ale (90.5% vs. 72.3%), and less likely to be married or living with a partn
er (14.4% vs. 36.2%) than those without MMUS. Patients with MMUS had over t
wice the rate of any current psychiatric disorder, almost two-and-a-half ti
mes the rate of any current anxiety disorder, and greater functional impair
ment. These data suggest that patients with MMUS are as common in urban pri
mary care clinics as in more affluent clinics and reinforce the need for PC
Ps to screen these patients for common and treatable psychiatric conditions
.