Tetrakis(dimethylamino)ethylene (TDAE) mediated addition of difluoromethylanions to heteroaryl thiocyanates. A new simple access to heteroaryl-SCF2Rderivatives

Authors
Billard, T Langlois, BR Medebielle, M
Citation
T. Billard et al., Tetrakis(dimethylamino)ethylene (TDAE) mediated addition of difluoromethylanions to heteroaryl thiocyanates. A new simple access to heteroaryl-SCF2Rderivatives, TETRAHEDR L, 42(20), 2001, pp. 3463-3465
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
20
Year of publication
2001
Pages
3463 - 3465
Database
ISI
SICI code
0040-4039(20010514)42:20<3463:T(MAOD>2.0.ZU;2-R
Abstract
New heteroaryl-SCF2R derivatives 8-13 are easily obtained in one-pot from t he tetrakis(dimethylamino)ethylene (TDAE) mediated reduction of halogenodif luoromethyl substrates RCF2X 1-4 in the presence of heteroaryl-thiocyanates 5-7. (C) 2001 Elsevier Science Ltd. All rights reserved.