Hepatic decompensation associated with lamivudine: A case report and review of lamivudine-induced hepatotoxicity

Authors
Ormseth, EJ Holtzmuller, KC Goodman, ZD Colonna, JO Batty, DS Sjogren, MH
Citation
Ej. Ormseth et al., Hepatic decompensation associated with lamivudine: A case report and review of lamivudine-induced hepatotoxicity, AM J GASTRO, 96(5), 2001, pp. 1619-1622
Citations number
15
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
AMERICAN JOURNAL OF GASTROENTEROLOGY
ISSN journal
00029270 → ACNP
Volume
96
Issue
5
Year of publication
2001
Pages
1619 - 1622
Database
ISI
SICI code
0002-9270(200105)96:5<1619:HDAWLA>2.0.ZU;2-A
Abstract
We report a case of a 62-yr-old man with chronic hepatitis B virus (HBV)-re lated cirrhosis who developed hepatic decompensation after being started on lamivudine requiring liver transplantation. Decompensated liver disease wh ile on lamivudine has been previously reported on two occasions, both HIV c oinfected patients on a combination of nucleoside analogues. Our patient is alive and well nearly 2 yr after successful liver transplantation. (C) 200 1 by Am. Cell.