Rosai-Dorfman disease presenting as bilateral lacrimal gland enlargement

PURPOSE: To report a patient with bilateral lacrimal gland enlargement as t he initial manifestation of Rosai-Dorfman disease, METHODS: Case report, RESULTS: A 14 year old female presented with left lacrimal gland enlargemen t followed by right lacrimal gland enlargement 11 weeks later, Bilateral la crimal gland biopsies were performed, and histopathologic examination revea led the diagnosis of Rosai-Dorfman disease. CONCLUSION: Patients with Rosai-Dorfman disease may present with bilateral lacrimal gland swelling in the absence of lymphadenopathy, Rosai-Dorfman di sease should be considered in the differential diagnosis of bilateral lacri mal gland enlargement. (C) 2001 by Elsevier Science Inc, All rights reserve d.