Objective: The objective of this study was to review findings from a previo
usly posited 'lock and key' hypothesis which challenge a number of assumpti
ons about cognitive theories of depression.
Method: A review of existing cognitive vulnerability theories is presented.
Two recent studies employed to test the lock and key hypothesis are summar
ized. The hypothesis is reviewed in light of other diathesis-stress models
of cognitive vulnerability.
Results: The identification of a depressed individual's core beliefs or cog
nitive schemas is a difficult task, with perhaps unresolvable difficulties
in disentangling any mood state determinant. Longitudinal assessment of ori
ginally euthymic subjects appears the best method to investigate any cognit
ive risk to depression and the significance of diathesis-stress models.
Conclusions: Empirical evidence for or against the validity of cognitive vu
lnerability theories is largely dependent upon the methodologies used to de
tect cognitive styles, as well as the nature of the subject groups studied.