Objective To identify a Dutch cohort of sildenafil users and describe their
baseline characteristics.
Patients and methods Each pharmacy in The Netherlands (n=1571) was asked to
identify prospectively the first 20 sildenafil prescriptions in their phar
macy over 1 year, and to complete and return a registration form. The colle
cted data included patient characteristics, the details of the sildenafil p
rescription (date, prescriber, number of prescriptions, dosing), and the us
e of co-medication by the patient in the year preceding the sildenafil pres
cription.
Results Data were collected from 4460 sildenafil prescriptions during the y
ear under study, relating to 3477 individual patients. Most of the cohort h
ad cardiovascular morbidity or diabetes. Sildenafil seems to have been used
by a new. previously untreated population of patients with erectile dysfun
ction. In addition, 69 men were identified who could have been using nitrat
es and sildenafil concomitantly.
Conclusion A cohort of patients using sildenafil was identified and charact
erized: they appeared to be representative of sildenafil users in The Nethe
rlands. This cohort will be followed prospectively to evaluate the medical
status (particularly cardiovascular) of the patients with time.