Role of chance in familial aggregation of colorectal cancer

Authors
Katballe, N Bentzen, SM Christensen, M Wikman, FP Orntoft, T Laurberg, S
Citation
N. Katballe et al., Role of chance in familial aggregation of colorectal cancer, BR J CANC, 84(8), 2001, pp. 1084-1086
Citations number
8
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
84
Issue
8
Year of publication
2001
Pages
1084 - 1086
Database
ISI
SICI code
0007-0920(20010420)84:8<1084:ROCIFA>2.0.ZU;2-L
Abstract
A prospective population-based study recorded family trees of 77 colorectal cancer patients younger than 50 years of age. Using mathematical modeling of population age-incidence data, we estimate that 1 (95% confidence limits 0 and 3) of these families is expected to meet the Amsterdam criteria I fo r HNPCC due to chance clustering of colorectal cancer. (C) 2001 Cancer Rese arch Campaign.