Immunohistochemical detection of ER beta in breast cancer: towards more detailed receptor profiling?

Authors
Skliris, GP Carder, PJ Lansdown, MRJ Speirs, V
Citation
Gp. Skliris et al., Immunohistochemical detection of ER beta in breast cancer: towards more detailed receptor profiling?, BR J CANC, 84(8), 2001, pp. 1095-1098
Citations number
13
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
84
Issue
8
Year of publication
2001
Pages
1095 - 1098
Database
ISI
SICI code
0007-0920(20010420)84:8<1095:IDOEBI>2.0.ZU;2-2
Abstract
Oestrogen receptor (ER) is used routinely to predict endocrine responsivene ss in patients with breast cancer. A second ER, ER beta has been described but its significance remains undefined; most studies have described mRNA le vels rather than protein expression. Here, we demonstrate for the first tim e, immunohistochemical detection of ER beta in archival breast tumours. (C) 2001 Cancer Research Campaign.