SYNTHESIS OF NEUTRAL, WATER-SOLUBLE CALIX[4]ARENES

Authors
GANSEY MHBG STEEMERS FJ VERBOOM W REINHOUDT DN
Citation
Mhbg. Gansey et al., SYNTHESIS OF NEUTRAL, WATER-SOLUBLE CALIX[4]ARENES, Synthesis, (6), 1997, pp. 643
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
6
Year of publication
1997
Database
ISI
SICI code
0039-7881(1997):6<643:SONWC>2.0.ZU;2-V
Abstract
Novel neutral water-soluble calix[4]arenes were synthesized via chloro sulfonylation of lower rim functionalized calix[4]arenes followed by r eaction with hydroxyl group containing amines. The solubility of these calix[4]arene sulfonamides in water varies from similar to 10(-5) to 3.1 . 10(-1) M. A route via hydrophobically protected amines improves the purification.