Disseminated infection and colonization by Scedosporium prolificans: A review of 18 cases, 1990-1999

Scedosporium prolificans infection was analyzed in 18 patients from whom th e fungus was isolated during the period 1990-1999. Of these 18 patients, 12 had some predisposing factor and either unconfirmed infection or colonizat ion, and 6 patients had confirmed disseminated infection: 4 patients with l eukemia died, 1 patient with breast cancer who underwent autologous bone ma rrow transplantation survived, and 1 patient with advanced acquired immunod eficiency syndrome died, although the fungal infection did not seem to affe ct his clinical symptoms.