Tl-201 uptake in bone and soft tissue involvement of sarcoidosis

The authors describe a 38-year-old man who was referred to the nuclear medi cine department because of pain and swelling of his fingers in both hands. Tc-99m MDP and Tl-201 scans were performed to evaluate the lesions. A Tc-99 m MDP bone scan showed hyperemia and increased uptake in the lesions. A Tl- 201 scan showed marked uptake in both early and delayed images in the lesio ns of his fingers. Bone biopsy and histologic examination confirmed sarcoid osis. This case indicates that Tl-201 uptake can be seen in bone lesions re sulting from sarcoidosis.