Programs devoted to the analysis of protein sequences exist either as stand
-alone programs or as Web servers. However, stand-alone programs can hardly
accommodate for the analysis that involves comparisons on databanks, which
require regular updates. Moreover, Web servers cannot be as efficient as s
tand-alone programs when dealing with real-time graphic display. We describ
e here a stand-atone software program called ANTHEPROT, which is intended t
o perform protein sequence analysis with a high integration level and clien
ts/server capabilities. It is an interactive program with a graphical user
interface that allows handling of protein sequence and data in a very inter
active and convenient manner. It provides many methods and tools, which are
integrated into a graphical user interface. ANTHEPROT is available for Win
dows-based systems. It is able to connect to a Web server in order to perfo
rm large-scale sequence comparison on up-to-date databanks. ANTHEPROT is fr
eely available to academic users and may be download at http://pbil.ibcp.fr
/ANTHEPROT. (C) 2001 Elsevier Science Ltd. All rights reserved.