BACKGROUND. The immediate effects of CO2 laser resurfacing include tissue a
blation and residual thermal damage. These laser-tissue interactions are sh
aped by parameters including fluence, dwell time, and number of passes.
OBJECTIVE. To assess the vaporization depth and residual thermal damage fol
lowing use of the "superficial" or "deep" scanning modes of a 40 W continuo
us wave CO2 laser using both frozen and paraffin sections.
METHODS. Fourteen subjects were divided into two groups for test treatments
in the right preauricular area with two passes of the laser. The "superfic
ial" mode parameters were 10 mm(2) scan, 200 mm lens, power 36 W, scan time
0.24 seconds, dwell time 0.22 msec, and fluence 5.5 J/cm(2). The "deep" mo
de settings were 9 mm(2) scan, 200 mm lens, power 18 W, scan time 0.64 seco
nds, dwell time 0.28 msec, and fluence 7.0 J/cm(2). The deep mode has a gre
ater pattern density than the superficial mode and also has a double patter
n of exposure. Biopsies encompassing equal areas of treated and untreated s
kin were taken immediately postoperatively and processed with both frozen a
nd paraffin-embedded techniques.
RESULTS. Vaporization depth was similar in both scanning modes and by both
tissue-processing techniques. On frozen sections, residual thermal damage w
as 20% greater in the deep mode than the superficial mode, but this was not
a statistically significant difference. There was no significant differenc
e between the two modes in the depth of thermal injury on paraffin sections
.
CONCLUSION. In keeping with theoretical expectations, vaporization depth wa
s similar in both treatment groups. No significant difference in residual t
hermal damage could be demonstrated between the two modes. However, the res
ults on frozen sections suggest that residual thermal damage may be greater
in the deep mode than in the superficial mode. In addition, frozen section
s may be more sensitive than paraffin sections in the detection of residual
thermal damage following laser resurfacing.