Study on liposomes by capillary electrophoresis

Liposomes made of mixtures of zwitterionic and anionic lipids were investig ated by means of capillary electrophoresis and dynamic light scattering. Th e influence of the molar lipid ratio and of the buffers, used in the runnin g electrolyte solution, on the physical characteristics of the liposomes we re investigated. Data on effective electrophoretic mobilities, total charge s as well as sizes of the liposomes are given. In addition, examples on the use of liposomes as carriers in electrokinetic capillary electrophoresis f or the separation of benzene derivatives, steroids, and phenols are shown.