Long-term effects of topiramate on bipolar mood instability, weight changeand glycemic control: a case-series

Authors
Chengappa, KNR Levine, J Rathore, D Parepally, H Atzert, R
Citation
Knr. Chengappa et al., Long-term effects of topiramate on bipolar mood instability, weight changeand glycemic control: a case-series, EUR PSYCHIA, 16(3), 2001, pp. 186-190
Citations number
11
Categorie Soggetti
Psychiatry,"Clinical Psycology & Psychiatry
Journal title
EUROPEAN PSYCHIATRY
ISSN journal
09249338 → ACNP
Volume
16
Issue
3
Year of publication
2001
Pages
186 - 190
Database
ISI
SICI code
0924-9338(200104)16:3<186:LEOTOB>2.0.ZU;2-J
Abstract
Topiramate is an antiepileptic agent, which is being investigated as a mood -stabilizer. Three obese individuals with DSM-IV bipolar I disorder and typ e II diabetes mellitus received topiramate treatment in combination with an tipsychotics and valproate or carbamazepine. In addition to improved mood s tability, these individuals lost between 16 to 20.5% of their pre-topiramat e body weight and also achieved significant glycemic control. (C) 2001 Edit ions scientifiques et medicales Elsevier SAS.